Finally, Pain Relief That Addresses the Source—Not Just the Symptoms

Living with chronic pain in Mesa changes everything. The drive down the 202 becomes unbearable. Weekend hikes at Usery Mountain Park feel like distant memories. Even simple tasks—playing with your grandchildren, gardening in your Queen Creek backyard, or sitting through your son’s baseball game at Red Mountain—become exercises in endurance rather than enjoyment.

You’re not alone. According to the Centers for Disease Control and Prevention, approximately 20.9% of American adults experience chronic pain, with Arizona residents facing additional challenges from our desert climate’s effects on joints and the active outdoor lifestyle that defines East Valley living.

Arizona Pain and Spine Institute offers comprehensive pain management in Mesa, AZ, with three East Valley locations. Board-certified physicians Dr. Asim Khan and Dr. Daniel Ryklin specialize in non-surgical, minimally invasive treatments including regenerative stem cell therapy, helping patients find lasting relief without surgery or long-term medication dependence.

An active senior adult walking comfortably on a scenic trail in Mesa, Arizona
Reclaiming your active lifestyle starts with addressing the root cause of your pain.

This guide covers what makes our Mesa pain management approach different, the treatments we offer, and how to take the first step toward reclaiming your active East Valley life.

Understanding Chronic Pain in Mesa and the East Valley

Chronic pain isn’t just a physical sensation—it’s a condition that affects every aspect of your life. When pain persists beyond the normal healing time (typically three to six months), it becomes chronic, creating changes in your nervous system that can make the pain feel permanent.

Get Back Your Normal Life Again

As pain specialists, we can guarantee that we are more than qualified in alleviating your pain and treating your condition.

What Causes Chronic Pain?

Mesa residents experience chronic pain from various sources:

  • Degenerative conditions: Arthritis, degenerative disc disease, and spinal stenosis worsen over time, particularly in Arizona’s dry climate
  • Injuries: Car accidents on the 60 and 202, sports injuries from hiking Superstition Mountains, or workplace incidents
  • Lower back pain: The most common complaint we see, affecting office workers, construction crews, and retirees alike
  • Sciatica: Nerve compression causing radiating leg pain that makes standing, walking, and sitting equally difficult
  • Failed back surgery syndrome: When previous spinal surgeries haven’t delivered the promised relief

Why Conventional Approaches Often Fall Short

If you’ve been living with chronic pain, you’ve likely experienced the frustrating cycle. Your primary care doctor prescribes pain medication that masks the symptoms temporarily. The orthopedic surgeon recommends surgery with months of recovery and uncertain outcomes. Physical therapy helps but doesn’t address the underlying problem.

Dr. Khan observes this pattern constantly among East Valley patients: “People come to us after years of taking medications that only provide temporary relief, or after being told surgery is their only option. There’s usually a better path.”

The opioid crisis has made this situation even more complex. While these medications have legitimate uses, long-term dependence creates additional problems. Arizona Pain and Spine Institute’s philosophy centers on treating pain at its source—not masking it with medications you’ll need indefinitely.

How Arizona Pain and Spine Institute Treats Pain Differently

Since co-founding the practice in 2016, Dr. Asim Khan and Dr. Daniel Ryklin have built Arizona Pain and Spine Institute around a simple principle: treat the cause of pain, not just the symptoms. This approach has drawn patients from across Arizona and neighboring states seeking alternatives to surgery and long-term medication.

Our Flagship: Regenerative Medicine

Regenerative medicine, particularly amniotic membrane stem cell therapy, represents the future of pain treatment. Unlike cortisone injections that provide temporary inflammation relief without healing damaged tissue, regenerative treatments work with your body’s natural repair mechanisms.

Here’s the difference: cortisone is like putting a bandage on a wound without cleaning it. Regenerative stem cell therapy actually promotes tissue repair at the cellular level, reducing inflammation while supporting genuine healing.

Diagram showing the mechanism of regenerative medicine on a damaged joint
Unlike temporary masks, regenerative therapy supports the body’s natural tissue repair process.

Dr. Ryklin explains: “We’re not just numbing the pain—we’re giving your body the biological tools it needs to repair damaged cartilage, reduce chronic inflammation, and restore function. Patients often see progressive improvement over weeks as the regenerative process continues.”

Interventional Pain Procedures

Our board-certified physicians perform precise, minimally invasive procedures using advanced imaging guidance:

  • Radiofrequency Ablation (RFA): Uses controlled heat to disrupt the nerve signals carrying pain messages to your brain, providing months to years of relief for facet joint pain and certain other conditions
  • Epidural Steroid Injections: Delivers anti-inflammatory medication directly to the source of spinal pain, reducing inflammation around irritated nerves
  • Joint Injections: Targets arthritic or injured knees, hips, and shoulders with precision-guided treatment
  • Nerve Blocks: Interrupts pain signals at specific nerve locations for diagnostic and therapeutic purposes
  • Trigger Point Injections: Releases muscle knots and tension patterns causing referred pain

Specialized Treatments

Beyond traditional pain management, we offer specialized services that set us apart:

Don’t let pain control your life. Schedule a consultation with Dr. Khan or Dr. Ryklin at Arizona Pain and Spine Institute. Call (480) 986-7246 or book online. Locations in East MesaMesa/Gilbert, and Queen Creek.

What to Expect as a Patient

Walking into a pain management clinic for the first time can feel intimidating, especially if previous treatments have disappointed you. Here’s exactly what happens when you become a patient at Arizona Pain and Spine Institute.

Your Initial Consultation

Dr. Khan and Dr. Ryklin take time to understand your complete pain picture. This isn’t a rushed 10-minute appointment where you’re handed a prescription and sent away. Your consultation includes a comprehensive review of your medical history and previous treatments, a detailed discussion of when the pain started and how it affects your daily life, physical examination and review of any imaging studies, and an honest conversation about treatment options—including what we can and cannot help with.

“We believe patients deserve to understand their condition and participate in treatment decisions,” says Dr. Khan. “If surgery is actually your best option, we’ll tell you. But most of the time, there are effective non-surgical alternatives patients don’t know exist.”

During Your Procedure

Most of our treatments are performed in-office using advanced imaging guidance (fluoroscopy or ultrasound) to ensure precise placement. You can expect procedures that typically take 15-30 minutes, local anesthesia to minimize discomfort, real-time imaging so Dr. Khan or Dr. Ryklin can visualize exactly where the treatment is being delivered, and same-day discharge—most patients drive themselves home.

Recovery and Results

Recovery varies by treatment. Injections may provide immediate relief, while regenerative treatments typically show progressive improvement over days to weeks as your body’s healing processes activate. Our team—including nurse practitioners Julia Tuleneva and Kaitlyn Spousta, PA—monitors your progress and adjusts your treatment plan as needed.

Insurance and FastTrack Access

Arizona Pain and Spine Institute works with most major insurance plans. However, we understand that insurance delays can keep you suffering for weeks or months. Our FastTrack program offers same-day cash-pay appointments, allowing you to bypass insurance authorization and start treatment immediately.

What Treatments Do Mesa Pain Management Doctors Offer?

Mesa pain management doctors at Arizona Pain and Spine Institute offer a comprehensive range of non-surgical treatments. These include regenerative stem cell therapy, radiofrequency ablation, epidural steroid injections, joint injections, nerve blocks, trigger point injections, Stellate Ganglion Block for PTSD, and Botox for chronic migraines.

Dr. Khan and Dr. Ryklin customize each treatment plan based on your specific condition, pain severity, and personal goals. During your consultation, they’ll explain which options offer the best chance of meaningful relief for your situation.

Does Insurance Cover Pain Management in Mesa?

Yes, most insurance plans cover pain management treatments in Mesa. Arizona Pain and Spine Institute accepts most major insurance carriers including Medicare and works directly with your insurance to maximize coverage. For patients facing authorization delays or high deductibles, our FastTrack cash-pay program provides same-day access to treatment.

Call (480) 986-7246 and our team will verify your specific coverage before your appointment.

How Do I Choose the Best Pain Management Clinic Near Me?

The best pain management clinic near you should have board-certified physicians, offer multiple treatment modalities beyond just medication, and take time to understand your specific condition. Look for doctors who specialize in interventional pain management rather than just prescribing pills, and who offer innovative options like regenerative medicine.

Arizona Pain and Spine Institute’s patient testimonials reflect our commitment to individualized care. Patients regularly travel from Chandler, Tempe, Scottsdale, and beyond because Dr. Khan and Dr. Ryklin deliver results that other approaches couldn’t achieve.

Why East Valley Patients Choose Arizona Pain and Spine Institute

Since 2016, patients throughout Mesa, Gilbert, Queen Creek, Chandler, Tempe, and Scottsdale have trusted Arizona Pain and Spine Institute for several key reasons.

Our doctors are fellowship-trained, board-certified pain management specialists—not general practitioners prescribing pain medication as a side service. We offer three convenient East Valley locations, eliminating long drives across Phoenix when you’re already in pain. Our treatment philosophy focuses on getting you off medications when possible and helping you avoid surgery.

Patients describe experiencing 70-80% pain reduction after treatments that previous providers said wouldn’t work. Others mention finally being able to golf again at courses like Longbow or Las Sendas. Veterans specifically seek us out for SGB treatment for PTSD. These results come from a practice built around actually solving pain problems rather than managing them indefinitely.

Take the First Step Toward Relief

Chronic pain doesn’t have to define your life in Mesa. Whether you’re dealing with lower back painknee arthritisneck pain, or a condition you’ve been told requires surgery, Dr. Khan and Dr. Ryklin can evaluate your options and create a personalized treatment plan.

You deserve more than temporary fixes and long-term medication dependence. You deserve doctors who will find the source of your pain and treat it effectively.

Call Arizona Pain and Spine Institute at (480) 986-7246 or schedule online. Locations in East MesaMesa/Gilbert, and Queen Creek.


Frequently Asked Questions

What conditions do pain management doctors in Mesa treat?

Pain management doctors in Mesa treat chronic conditions including lower back pain, sciatica, herniated discs, arthritis, neck pain, migraines, neuropathy, and post-surgical pain. At Arizona Pain and Spine Institute, Dr. Khan and Dr. Ryklin also specialize in treating PTSD and anxiety using Stellate Ganglion Block therapy.

Is pain management the same as being prescribed pain medication?

No. True pain management focuses on treating the source of pain, not just masking symptoms with medication. Dr. Khan and Dr. Ryklin’s goal at Arizona Pain and Spine Institute is to reduce or eliminate your need for pain medications through treatments like regenerative stem cell therapy, nerve blocks, and radiofrequency ablation.

How quickly can I get an appointment at a Mesa pain clinic?

Arizona Pain and Spine Institute offers same-day appointments through our FastTrack cash-pay program, bypassing insurance authorization delays. For insurance-based appointments, we typically schedule new patients within one to two weeks at our East Mesa, Mesa/Gilbert, or Queen Creek locations.

Do I need a referral to see a pain management doctor in Mesa, AZ?

Most patients do not need a referral to schedule with Arizona Pain and Spine Institute, though some insurance plans may require one for coverage. Call (480) 986-7246 and our team will verify your specific insurance requirements before your appointment.

What is regenerative medicine and is it available in Mesa?

Regenerative medicine uses biological materials like amniotic membrane stem cells to promote tissue repair and reduce inflammation—rather than just masking pain temporarily. Dr. Khan and Dr. Ryklin offer regenerative stem cell therapy at all three East Valley locations as an alternative to cortisone injections and surgery.


The statements on this blog are not intended to diagnose, treat, cure, or prevent any disease. The information provided reflects published medical research and Arizona Pain and Spine Institute’s clinical expertise. Individual results vary based on condition, severity, and treatment response. Always consult Dr. Khan, Dr. Ryklin, or your personal physician for specific medical advice. For appointments, call (480) 986-7246 or visit gotpainarizona.com.