Living with chronic pain changes everything. Whether it’s knee pain that stops you from hiking the trails at Riparian Preserve, shoulder stiffness that makes yard work impossible, or back pain that turns your commute on the 202 into agony—you deserve more than temporary fixes and prescription refills.

Arizona Pain and Spine Institute offers regenerative medicine in Gilbert, AZ, including amniotic stem cell therapy and PRP injections. Dr. Asim Khan and Dr. Daniel Ryklin use these advanced treatments to reduce inflammation, promote tissue repair, and provide lasting pain relief without surgery or long-term medication dependence.

According to the CDC, approximately 20.9% of American adults live with chronic pain—and Arizona residents are no exception. At Arizona Pain and Spine Institute, we believe you shouldn’t have to choose between invasive surgery and a lifetime of medications. Our Mesa/Gilbert location brings cutting-edge regenerative medicine directly to the East Valley community.

This page explains how regenerative medicine works, what treatments we offer Gilbert patients, and why Dr. Khan and Dr. Ryklin have become the trusted choice for non-surgical pain relief across Gilbert, Mesa, Queen Creek, and the greater Phoenix metro area.

What Is Regenerative Medicine?

Regenerative medicine represents a fundamental shift in how we treat chronic pain. Rather than masking symptoms with medications or replacing joints through surgery, regenerative treatments work with your body’s natural healing processes to repair damaged tissue at the cellular level.

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As pain specialists, we can guarantee that we are more than qualified in alleviating your pain and treating your condition.

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Traditional pain management often relies on cortisone injections that provide temporary relief—typically lasting weeks to months—before the pain returns. Cortisone reduces inflammation but doesn’t address the underlying tissue damage. Over time, repeated cortisone injections can actually weaken tendons and cartilage.

Regenerative medicine takes a different approach. Treatments like amniotic stem cell therapy and platelet-rich plasma (PRP) deliver concentrated healing factors directly to damaged tissue. These biological materials contain growth factors, cytokines, and cellular components that reduce inflammation while simultaneously promoting tissue regeneration.

Research published in the Journal of Pain Research demonstrates that regenerative therapies can provide significant, lasting improvement for conditions including osteoarthritis, tendon injuries, and degenerative disc disease—conditions that historically required surgical intervention.

Why Gilbert Residents Choose Regenerative Medicine

Gilbert’s active lifestyle creates specific demands on joints and connective tissue. Weekend soccer at Freestone Park, golf at Western Skies, hiking at San Tan Mountain Regional Park—these activities keep East Valley residents healthy but can accelerate joint wear and soft tissue injuries.

The desert climate compounds these challenges. Arizona’s dry heat can affect joint lubrication and connective tissue elasticity, particularly for residents over 40. Many Gilbert patients come to us after years of managing pain with over-the-counter medications, frustrated that conventional treatments haven’t provided lasting relief.

Regenerative medicine offers these patients a third option: real tissue repair without the risks, recovery time, and uncertainty of surgical procedures.

Regenerative Medicine Treatments at Arizona Pain and Spine Institute

Dr. Asim Khan and Dr. Daniel Ryklin co-founded Arizona Pain and Spine Institute in 2016 with a clear mission: provide effective pain relief through minimally invasive treatments that address pain at its source. Regenerative medicine has become the cornerstone of that mission.

Amniotic Stem Cell Therapy

Amniotic membrane stem cell therapy is Arizona Pain and Spine Institute’s flagship regenerative treatment. This advanced therapy uses concentrated biological material derived from donated amniotic tissue—collected ethically from consenting mothers during scheduled cesarean deliveries—to deliver powerful healing factors directly to damaged joints and tissue.

Amniotic tissue contains:

  • Mesenchymal stem cells that can differentiate into cartilage, bone, and connective tissue
  • Growth factors that stimulate cellular repair and new tissue formation
  • Anti-inflammatory cytokines that reduce swelling and pain at the treatment site
  • Hyaluronic acid that lubricates joints and supports cartilage health

Dr. Khan explains: “What makes amniotic stem cell therapy different from cortisone is that we’re not just turning down the volume on pain signals—we’re actually providing the building blocks your body needs to repair damaged tissue. Patients experience lasting improvement because we’re treating the underlying problem, not just the symptoms.”

Amniotic stem cell therapy is performed as an outpatient procedure using imaging guidance for precise placement. Most Gilbert patients return to normal activities the same day, with full therapeutic effects developing over the following weeks as cellular repair progresses.

Platelet-Rich Plasma (PRP) Therapy

PRP therapy uses your own blood to create a concentrated healing solution. We draw a small blood sample, process it in a centrifuge to isolate platelets and growth factors, then inject this concentrated preparation directly into the treatment area.

According to the Mayo Clinic, PRP contains growth factors that can accelerate tissue healing and reduce inflammation. Because PRP uses your own biological material, there’s virtually no risk of rejection or allergic reaction.

Dr. Ryklin specializes in using PRP for tendon injuries, ligament damage, and early-stage osteoarthritis. “For many patients, PRP provides an excellent middle ground,” Dr. Ryklin notes. “It’s less involved than stem cell therapy but significantly more effective than cortisone for promoting actual tissue repair.”

Conditions We Treat with Regenerative Medicine

Gilbert patients seek regenerative medicine treatment for a wide range of conditions:

  • Knee pain — osteoarthritis, meniscus tears, ligament injuries, runner’s knee
  • Hip pain — hip arthritis, labral tears, bursitis
  • Shoulder pain — rotator cuff injuries, frozen shoulder, tendinitis
  • Lower back pain — degenerative disc disease, facet joint arthritis, sacroiliac dysfunction
  • Sports injuries — tennis elbow, Achilles tendinitis, plantar fasciitis

Ready to explore regenerative medicine for your pain? Dr. Khan and Dr. Ryklin offer personalized consultations to determine if stem cell therapy or PRP is right for your condition. Call (480) 986-7246 or schedule online. Convenient locations in Mesa, Gilbert, and Queen Creek.

What Makes Arizona Pain and Spine Institute Different

Gilbert has options for pain management. What brings patients to Arizona Pain and Spine Institute—often from across Arizona and neighboring states—is our commitment to treating pain at its source through the most advanced non-surgical methods available.

Board-Certified Pain Specialists

Dr. Asim Khan and Dr. Daniel Ryklin are both board-certified in pain management with extensive training in interventional procedures and regenerative medicine. Since co-founding the practice in 2016, they’ve treated thousands of patients who had been told surgery was their only option.

Our clinical team includes experienced nurse practitioners and physician assistants—Julia Tuleneva (NP), Kaitlyn Spousta (PA), and Meghan (PA)—who work alongside Dr. Khan and Dr. Ryklin to provide comprehensive, coordinated care.

The Non-Surgical Philosophy

Arizona Pain and Spine Institute exists as an alternative to surgery and long-term medication dependence. Dr. Khan and Dr. Ryklin’s goal is to get you off medications when possible and provide natural solutions that support your body’s healing capacity.

This philosophy shapes every treatment decision. Before recommending any procedure, we explore the full range of minimally invasive options. Many patients who come to us expecting to need surgery leave with a treatment plan that avoids the operating room entirely.

Comprehensive Treatment Integration

Regenerative medicine often works best as part of a multi-faceted treatment approach. Depending on your condition, Dr. Khan and Dr. Ryklin may combine stem cell or PRP therapy with:

FastTrack Same-Day Access

We understand that chronic pain doesn’t wait for insurance approval. Our FastTrack cash-pay program allows Gilbert patients to schedule same-day appointments without waiting weeks for insurance authorization. You’ll see Dr. Khan or Dr. Ryklin directly, receive a complete evaluation, and—in many cases—begin treatment the same day.

What to Expect as a Gilbert Patient

Your regenerative medicine journey at Arizona Pain and Spine Institute begins with a comprehensive consultation at our Mesa/Gilbert location, conveniently located for patients throughout the East Valley.

Your Initial Consultation

Dr. Khan or Dr. Ryklin will take time to understand your complete pain history—not just where it hurts, but how pain affects your daily life, what treatments you’ve tried, and what your goals are for treatment. We review any imaging studies you bring and may order additional diagnostics if needed.

This consultation typically lasts 30–45 minutes. We believe rushing this step leads to incomplete treatment plans. You’ll leave with a clear understanding of what’s causing your pain and which treatment options offer the best path to relief.

The Treatment Experience

Regenerative medicine procedures at Arizona Pain and Spine Institute are performed in our comfortable, state-of-the-art treatment suites using imaging guidance (fluoroscopy or ultrasound) for precise placement.

For amniotic stem cell therapy:

  • The treatment area is cleaned and numbed with local anesthetic
  • Using imaging guidance, Dr. Khan or Dr. Ryklin injects the amniotic material directly into the damaged tissue
  • The entire procedure typically takes 15–30 minutes
  • Most patients drive themselves home and return to daily activities the same day

For PRP therapy:

  • We draw a small blood sample (similar to routine lab work)
  • Your blood is processed in a centrifuge for approximately 15 minutes
  • The concentrated PRP is injected into the treatment area using imaging guidance
  • Total appointment time is typically 45–60 minutes

Recovery and Results

Unlike surgery, regenerative medicine requires minimal recovery time. Most patients experience some mild soreness at the injection site for 24–48 hours. We recommend avoiding strenuous activity for 1–2 weeks to allow the healing process to begin.

Results timeline: Because regenerative treatments work by stimulating your body’s natural repair processes, full benefits develop gradually. Most patients notice meaningful improvement within 2–6 weeks, with continued progress over the following 2–3 months as tissue regeneration continues.

Dr. Khan and Dr. Ryklin schedule follow-up appointments to monitor your progress and adjust your treatment plan as needed. Some patients achieve excellent results with a single treatment; others benefit from a series of injections spaced several weeks apart.

Insurance and Payment Options

Arizona Pain and Spine Institute works with most major insurance plans. Our billing team will verify your coverage and explain your benefits before treatment.

For patients who prefer not to use insurance—or whose plans don’t cover regenerative therapies—our FastTrack cash-pay program provides transparent pricing and same-day scheduling. Contact our office at (480) 986-7246 to discuss payment options.

Does Stem Cell Therapy Really Work for Chronic Pain?

Yes, clinical research supports the effectiveness of stem cell therapy for many chronic pain conditions. A systematic review published in Pain Research and Management found that regenerative therapies produced significant improvement in pain scores and functional outcomes for patients with osteoarthritis and other degenerative conditions.

At Arizona Pain and Spine Institute, Dr. Khan and Dr. Ryklin have observed consistent results in their Gilbert-area patients. Many patients who had been told they needed joint replacement surgery have experienced substantial pain relief and improved function through amniotic stem cell therapy—often delaying or avoiding surgery entirely.

Individual results vary based on condition severity, overall health, and treatment response. During your consultation, Dr. Khan or Dr. Ryklin will review your specific situation and provide realistic expectations for your treatment outcomes.

How Much Does Regenerative Medicine Cost in Arizona?

Regenerative medicine costs vary based on the specific treatment, the area being treated, and the number of sessions recommended. Arizona Pain and Spine Institute provides detailed cost information during your consultation after Dr. Khan or Dr. Ryklin evaluates your condition and develops a personalized treatment plan.

While some insurance plans cover certain regenerative therapies, many classify these treatments as elective. Our FastTrack cash-pay program offers an alternative for patients seeking immediate treatment without insurance delays. We also offer flexible payment arrangements to make regenerative medicine accessible to Gilbert patients.

Contact our office at (480) 986-7246 to discuss pricing and payment options for your specific situation.

What Conditions Can Be Treated with PRP Injections?

PRP injections are effective for a wide range of musculoskeletal conditions, particularly those involving tendons, ligaments, and joints. Common conditions Dr. Khan and Dr. Ryklin treat with PRP include:

  • Tennis elbow and golfer’s elbow
  • Achilles tendinitis
  • Plantar fasciitis
  • Rotator cuff injuries
  • Patellar tendinitis (jumper’s knee)
  • Mild to moderate knee osteoarthritis
  • Hip bursitis
  • Ligament sprains

PRP is particularly well-suited for active Gilbert residents dealing with overuse injuries or early-stage joint degeneration. The treatment uses your body’s own healing factors, making it an excellent option for patients who want a natural approach to pain relief.

Schedule a consultation at our Mesa/Gilbert location to determine if PRP is appropriate for your condition.

Serving Gilbert and the East Valley Community

Arizona Pain and Spine Institute’s Mesa/Gilbert location provides convenient access to regenerative medicine for patients throughout the East Valley. We’re easily accessible from:

  • Gilbert — via the 202 or Gilbert Road
  • Mesa — minutes from downtown Mesa and the Superstition Springs area
  • Queen Creek — also served by our Queen Creek location
  • Chandler — quick access via the 202
  • Tempe and Scottsdale — also served by our East Mesa location

Arizona Pain and Spine Institute
Phone: (480) 986-7246
Website: gotpainarizona.com
Locations: East Mesa · Mesa/Gilbert · Queen Creek

Take the First Step Toward Lasting Pain Relief

Chronic pain doesn’t have to define your life. Regenerative medicine offers Gilbert residents a path to genuine healing—not just symptom management, but actual tissue repair that can restore function and reduce dependence on pain medications.

Dr. Asim Khan and Dr. Daniel Ryklin have helped thousands of East Valley patients find relief through amniotic stem cell therapy, PRP injections, and other advanced non-surgical treatments. Whether you’re dealing with joint pain, a nagging sports injury, or degenerative conditions you’ve been told require surgery, we’re here to explore every option with you.

Call (480) 986-7246 or schedule your consultation online. Convenient locations in Mesa, Gilbert, and Queen Creek. Same-day appointments available through our FastTrack program.

Frequently Asked Questions

Is regenerative medicine available in Gilbert, Arizona?

Yes, Arizona Pain and Spine Institute offers regenerative medicine at our Mesa/Gilbert location, serving patients throughout Gilbert and the East Valley. Dr. Khan and Dr. Ryklin provide amniotic stem cell therapy and PRP injections for joint pain, arthritis, tendon injuries, and other conditions. Call (480) 986-7246 to schedule.

How long does it take for stem cell therapy to work?

Most patients notice meaningful improvement within 2–6 weeks after stem cell therapy, with continued progress over 2–3 months as tissue regeneration continues. Because regenerative treatments stimulate your body’s natural healing processes, results develop gradually rather than immediately. Dr. Khan and Dr. Ryklin monitor your progress through follow-up appointments.

Can regenerative medicine help me avoid knee replacement surgery?

Many patients have delayed or avoided knee replacement surgery through regenerative medicine. Amniotic stem cell therapy and PRP can reduce inflammation and promote cartilage repair in arthritic knees. Dr. Khan and Dr. Ryklin evaluate each patient’s condition to determine if regenerative treatment is appropriate for their specific situation.

Does insurance cover stem cell therapy in Arizona?

Insurance coverage for regenerative medicine varies by plan. Some insurers cover certain treatments while others classify them as elective. Arizona Pain and Spine Institute’s billing team verifies your coverage before treatment. Our FastTrack cash-pay program offers same-day access for patients who prefer not to wait for insurance authorization.

What’s the difference between PRP and stem cell therapy?

PRP uses growth factors from your own blood to promote healing, while amniotic stem cell therapy delivers concentrated stem cells and healing factors from donated tissue. Both reduce inflammation and support tissue repair. Dr. Khan and Dr. Ryklin recommend the appropriate treatment based on your specific condition and goals.

The statements on this blog are not intended to diagnose, treat, cure, or prevent any disease. The information provided reflects published medical research and Arizona Pain and Spine Institute’s clinical expertise. Individual results vary based on condition, severity, and treatment response. Always consult Dr. Khan, Dr. Ryklin, or your personal physician for specific medical advice. For appointments, call (480) 986-7246 or visit gotpainarizona.com.